Qbrexza for excessive underarm sweating

At a glance

How it works

It blocks a nerve signal that tells sweat glands to work. Most of the effect stays near the skin where you apply it.

Who it is for

Qbrexza is approved for excessive underarm sweating in adults and children age 9 and older. The main studies, ATMOS-1 and ATMOS-2, tested underarm use.

What the studies measured

ATMOS-1 and ATMOS-2 compared Qbrexza with an inactive cloth. The studies measured daily symptom scores and the weight of sweat after four weeks.

How to apply

Use one cloth once a day for both underarms. Wipe one underarm with one side, then the other underarm with the other side. Throw the cloth away and wash your hands. Keep the medicine out of your eyes.

Common side effects

Dry or irritated skin and dry mouth are common. Blurred vision, a widened pupil, constipation, or trouble urinating can also occur. Eye contact can affect one pupil for a time.

When it may not be safe

Tell the prescriber if you have glaucoma, severe dry mouth, constipation, or trouble emptying your bladder. The full prescribing information lists the conditions that need extra care.

What to consider

• • Type: single-use prescription cloth
• • Schedule: once daily for both underarms
• • Prescription required
• • FDA-approved use: underarm sweating, age 9+
• • Body area: underarms only

Side effects and reasons this may not be safe for you

• • Application-site dryness, irritation, erythema
• • Dry mouth (sweat-reducing medicine)
• • Pupil widening (pupil dilation) if eye contact occurs
• • Urinary hesitation
• • Blurred vision
• • Constipation (less common)

Compare this option

• Compare: qbrexza vs sofdra →

Sources for this treatment

Important numbers and approved uses on this page link back to the research or official information that supports them.

Frequently asked

Can I use Qbrexza on my hands or feet?

No. Qbrexza is approved only for underarms. Hand and foot sweating have other options, including iontophoresis.

How does Qbrexza compare to Sofdra?

Both are once-daily prescription treatments for underarm sweating in people age 9 and older. Qbrexza is a cloth. Sofdra is a gel. See the comparison for study results, directions, and side effects.

Will my pupils stay dilated if I get the product in my eye?

Eye contact can widen one pupil and blur close vision for a time. Wash your hands after applying Qbrexza and avoid touching your eyes.

Read next

• Check my sweating →
• Where sweating happens →
• How we research our guides →

Where this fits